Principais Artigos Científicos

  1. von Muhlen CA, Karayev D, Metzger A. Update on autoantibodies in necrotizing myopathies, with special regard to anti-HMGCR. In Conrad K, Andrade LEC, Chan EKL et al (editors), Immunodeficiency, Infection and Autoimmune Diseases: Report on the 13th Dresden Symposium on Autoantibodies, Dresden (Germany), p. 350, 2017 (electronic media, Autoantigens, Autoantibodies, Autoimmunity volume 11).
  2. GEO-RA Group. Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clin Rheumatol. 2017 Mar;36(3):485-497. doi: 10.1007/s10067-016-3481-9. Epub 2016 Dec 19. PubMed PMID: 27995382.
  3. Kowal-Bielecka O, Fransen J, Avouac J, Becker M, Kulak A, Allanore Y, Distler O, Clements P, Cutolo M, Czirjak L, Damjanov N, Del Galdo F, Denton CP, Distler JHW, Foeldvari I, Figelstone K, Frerix M, Furst DE, Guiducci S, Hunzelmann N, Khanna D, Matucci-Cerinic M, Herrick AL, van den Hoogen F, van Laar JM, Riemekasten G, Silver R, Smith V, Sulli A, Tarner I, Tyndall A, Welling J, Wigley F, Valentini G, Walker UA, Zulian F, Müller-Ladner U; EUSTAR Coauthors. Update of EULAR recommendations for the treatment of systemic sclerosis. Ann Rheum Dis. 2017 Aug;76(8):1327-1339. doi: 10.1136/annrheumdis-2016-209909. Epub 2016 Nov 9. PubMed PMID: 27941129.
  4. Chan EK, Damoiseaux J, de Melo Cruvinel W, Carballo OG, Conrad K, Francescantonio PL, Fritzler MJ, Garcia-De La Torre I, Herold M, Mimori T, Satoh M, von Mühlen CA, Andrade LE. Report on the second International Consensus on ANA Pattern (ICAP) workshop in Dresden 2015. Lupus. 2016 Jul;25(8):797-804. doi: 10.1177/0961203316640920. PubMed PMID: 27252255.
  5. Damoiseaux J, von Mühlen CA, Garcia-De La Torre I, Carballo OG, de Melo Cruvinel W, Francescantonio PL, Fritzler MJ, Herold M, Mimori T, Satoh M, Andrade LE, Chan EK, Conrad K. International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results. Auto Immun Highlights. 2016 Dec;7(1):1. doi: 10.1007/s13317-016-0075-0. Epub 2016 Jan 30. PubMed PMID: 26831867; PubMed Central PMCID: PMC4733811.
  6. Chan EK, Damoiseaux J, Carballo OG, Conrad K, de Melo Cruvinel W, Francescantonio PL, Fritzler MJ, Garcia-De La Torre I, Herold M, Mimori T, Satoh M, von Mühlen CA, Andrade LE. Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014-2015. Front Immunol. 2015 Aug 20;6:412. doi: 10.3389/fimmu.2015.00412. eCollection 2015. Review. PubMed PMID: 26347739; PubMed Central PMCID: PMC4542633.
  7. Wirz EG, Jaeger VK, Allanore Y, Riemekasten G, Hachulla E, Distler O, Airò P, Carreira PE, Tikly M, Vettori S, Balbir Gurman A, Damjanov N, Müller-Ladner U, Distler J, Li M, Häusermann P, Walker UA; EUSTAR coauthors. Incidence and predictors of cutaneous manifestations during the early course of systemic sclerosis: a 10-year longitudinal study from the EUSTAR database. Ann Rheum Dis. 2016 Jul;75(7):1285-92. doi: 10.1136/annrheumdis-2015-207271. Epub 2015 Jul 31. PubMed PMID: 26232495.
  8. Mihai C, Landewé R, van der Heijde D, Walker UA, Constantin PI, Gherghe AM, Ionescu R, Rednic S, Allanore Y, Avouac J, Czirják L, Hachulla E, Riemekasten G, Cozzi F, Airò P, Cutolo M, Mueller-Ladner U, Matucci-Cerinic M; EUSTAR co-authors. Digital ulcers predict a worse disease course in patients with systemic sclerosis. Ann Rheum Dis. 2016 Apr;75(4):681-6. doi: 10.1136/annrheumdis-2014-205897. Epub 2015 Feb 16. PubMed PMID: 25688073.
  9. Francescantonio PL, Cruvinel Wde M, Dellavance A, Andrade LE, Taliberti BH, von Mühlen CA, Bichara CD, Bueno C, Mangueira CL, Carvalho DG, Bonfá ES, Brito Fde A, Araújo FI, Rêgo J, Pereira KM, dos Anjos LM, Bissoli Mde F, Santiago MB, Maluf NZ, Alvarenga RR, Neves SP, Valim V, dos Santos WS. IV Brazilian guidelines for autoantibodies on HEp-2 cells. Rev Bras Reumatol. 2014 Jan-Feb;54(1):44-50. English, Portuguese. PubMed PMID: 24878791.
  10. Carcamo WC, Calise SJ, von Mühlen CA, Satoh M, Chan EK. Molecular cell biology and immunobiology of mammalian rod/ring structures. Int Rev Cell Mol Biol. 2014;308:35-74. doi: 10.1016/B978-0-12-800097-7.00002-6. Review. PubMed PMID: 24411169.
  11. Elhai M, Meunier M, Matucci-Cerinic M, Maurer B, Riemekasten G, Leturcq T, Pellerito R, Von Mühlen CA, Vacca A, Airo P, Bartoli F, Fiori G, Bokarewa M, Riccieri V, Becker M, Avouac J, Müller-Ladner U, Distler O, Allanore Y; EUSTAR (EULAR Scleroderma Trials and Research group). Outcomes of patients with systemic sclerosis-associated polyarthritis and myopathy treated with tocilizumab or abatacept: a EUSTAR observational study. Ann Rheum Dis. 2013 Jul;72(7):1217-20. doi: 10.1136/annrheumdis-2012-202657. Epub 2012 Dec 19. PubMed PMID: 23253926.
  12. Meier FM, Frommer KW, Dinser R, Walker UA, Czirjak L, Denton CP, Allanore Y, Distler O, Riemekasten G, Valentini G, Müller-Ladner U; EUSTAR Co-authors. Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database. Ann Rheum Dis. 2012 Aug;71(8):1355-60. doi: 10.1136/annrheumdis-2011-200742. Epub 2012 May 21. PubMed PMID: 22615460.
  13. Covini G, Carcamo WC, Bredi E, von Mühlen CA, Colombo M, Chan EK. Cytoplasmic rods and rings autoantibodies developed during pegylated interferon and ribavirin therapy in patients with chronic hepatitis C. Antivir Ther. 2012;17(5):805-11. doi: 10.3851/IMP1993. Epub 2011 Dec 1. PubMed PMID: 22293655.
  14. Carcamo WC, Satoh M, Kasahara H, Terada N, Hamazaki T, Chan JY, Yao B, Tamayo S, Covini G, von Mühlen CA, Chan EK. Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells. PLoS One. 2011;6(12):e29690. doi: 10.1371/journal.pone.0029690. Epub 2011 Dec 29. PubMed PMID: 22220215; PubMed Central PMCID: PMC3248424.
  15. Rigby W, Tony HP, Oelke K, Combe B, Laster A, von Muhlen CA, Fisheleva E, Martin C, Travers H, Dummer W. Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a forty-eight-week randomized, double-blind, placebo-controlled, parallel-group phase III trial. Arthritis Rheum. 2012 Feb;64(2):350-9. doi: 10.1002/art.33317. PubMed PMID: 21905001.
  16. Medeiros AM, von Mühlen CA, Gidlund MA, Bodanese R, Gottlieb MG, Bodanese LC. Antibodies against oxLDL and acute coronary syndrome. Arq Bras Cardiol. 2010 Jul;95(1):47-54. Epub 2010 Jun 11. PubMed PMID: 20563523.
  17. Tyndall AJ, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, Bancel DF, Allanore Y, Müller-Ladner U, Distler O, Iannone F, Pellerito R, Pileckyte M, Miniati I, Ananieva L, Gurman AB, Damjanov N, Mueller A, Valentini G, Riemekasten G, Tikly M, Hummers L, Henriques MJ, Caramaschi P, Scheja A, Rozman B, Ton E, Kumánovics G, Coleiro B, Feierl E, Szucs G, Von Mühlen CA, Riccieri V, Novak S, Chizzolini C, Kotulska A, Denton C, Coelho PC, Kötter I, Simsek I, de la Pena Lefebvre PG, Hachulla E, Seibold JR, Rednic S, Stork J, Morovic-Vergles J, Walker UA. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann Rheum Dis. 2010 Oct;69(10):1809-15. doi: 10.1136/ard.2009.114264. Epub 2010 Jun 15. PubMed PMID: 20551155.
  18. Bender AL, da Silveira IG, von Mühlen CA, Staub HL. High specificity but low sensitivity of the cartilage oligomeric matrix protein (COMP) test in rheumatoid arthritis and osteoarthritis. Clin Chem Lab Med. 2010 Apr;48(4):569-70. doi: 10.1515/CCLM.2010.081. PubMed PMID: 20148721.
  19. Andrade FD, Bender AL, da Silveira IG, Stein H, von Mühlen CA, Staub HL. Cartilage oligomeric matrix protein/thrombospondin-5 (COMP/TSP-5) levels do not correlate to functional class in patients with rheumatoid arthritis. Clin Rheumatol. 2009 Dec;28(12):1441-2. doi: 10.1007/s10067-009-1255-3. Epub 2009 Aug 30. PubMed PMID: 19727918.
  20. Dugan EM, Huber AM, Miller FW, Rider LG; International Myositis Assessment and Clinical Studies Group. Photoessay of the cutaneous manifestations of the idiopathic inflammatory myopathies. Dermatol Online J. 2009 Feb 15;15(2):1. Review. PubMed PMID: 19336018.
  21. Recuero ML, Silva JB, Norman GL, von Mühlen CA, Staub HL. IgA antibodies to beta2-glycoprotein I and carotid disease. Isr Med Assoc J. 2007 Aug;9(8):631-2. PubMed PMID: 17879466.
  22. Kessenbrock K, Fritzler MJ, Groves M, Eissfeller P, von Mühlen CA, Höpfl P, Mahler M. Diverse humoral autoimmunity to the ribosomal P proteins in systemic lupus erythematosus and hepatitis C virus infection. J Mol Med (Berl). 2007 Sep;85(9):953-9. Epub 2007 Aug 1. PubMed PMID: 17668158.
  23. Franck M, Staub HL, Petracco JB, Norman GL, Lassen AJ, Schiavo N, Borges RB, von Mühlen CA. Autoantibodies to the atheroma component beta2-glycoprotein I and risk of symptomatic peripheral artery disease. Angiology. 2007 Jun-Jul;58(3):295-302. PubMed PMID: 17626983.
  24. Silveira IG, Burlingame RW, von Mühlen CA, Bender AL, Staub HL. Anti-CCP antibodies have more diagnostic impact than rheumatoid factor (RF) in a population tested for RF. Clin Rheumatol. 2007 Nov;26(11):1883-9. Epub 2007 Apr 5. PubMed PMID: 17410320.
  25. Staub HL, Franck M, Ranzolin A, Norman GL, Iverson GM, von Mühlen CA. IgA antibodies to beta2-glycoprotein I and atherosclerosis. Autoimmun Rev. 2006 Dec;6(2):104-6. Epub 2006 Jul 24. Review. PubMed PMID: 17138253.
  26. Iverson GM, von Mühlen CA, Staub HL, Lassen AJ, Binder W, Norman GL. Patients with atherosclerotic syndrome, negative in anti-cardiolipin assays, make IgA autoantibodies that preferentially target domain 4 of beta2-GPI. J Autoimmun. 2006 Dec;27(4):266-71. Epub 2006 Oct 31. PubMed PMID: 17081732.
  27. Staub HL, von Muhlen CA, Norman GL. Beta2-glycoprotein I IgA antibodies and ischaemic stroke. Rheumatology (Oxford). 2006 May;45(5):645-6; author reply 646. Epub 2006 Feb 21. PubMed PMID: 16492682.
  28. Mahler M, Kessenbrock K, Szmyrka M, Takasaki Y, Garcia-De La Torre I, Shoenfeld Y, Hiepe F, Shun-le C, von Mühlen CA, Locht H, Höpfl P, Wiik A, Reeves W, Fritzler MJ. International multicenter evaluation of autoantibodies to ribosomal P proteins. Clin Vaccine Immunol. 2006 Jan;13(1):77-83. PubMed PMID: 16426003; PubMed Central PMCID: PMC1356623.
  29. Martins TB, Burlingame R, von Mühlen CA, Jaskowski TD, Litwin CM, Hill HR. Evaluation of multiplexed fluorescent microsphere immunoassay for detection of autoantibodies to nuclear antigens. Clin Diagn Lab Immunol. 2004 Nov;11(6):1054-9. PubMed PMID: 15539505; PubMed Central PMCID: PMC524771.
  30. Ranzolin A, Bohn JM, Norman GL, Manenti E, Bodanese LC, von Mühlen CA, Staub HL. Anti-beta2-glycoprotein I antibodies as risk factors for acute myocardial infarction. Arq Bras Cardiol. 2004 Aug;83(2):141-4; 137-40. Epub 2004 Aug 17. English, Portuguese. PubMed PMID: 15322656.
  31. Nozawa K, Fritzler MJ, von Mühlen CA, Chan EK. Giantin is the major Golgi autoantigen in human anti-Golgi complex sera. Arthritis Res Ther. 2004;6(2):R95-102. Epub 2003 Dec 15. PubMed PMID: 15059272; PubMed Central PMCID: PMC400427.
  32. Munari L, Charchat S, Rodrigues L, von Muhlen CA, Baú AR, Lavinsky L, Bonorino C. An ELISA serum assay for autoantibodies to HSP70 in immune-mediated hearing loss. J Immunol Methods. 2003 Dec;283(1-2):155-61. PubMed PMID: 14659907.
  33. Staub HL, Norman GL, Crowther T, da Cunha VR, Polanczyk A, Bohn JM, Fernandes JG, Chahade WH, von Mühlen CA. Antibodies to the atherosclerotic plaque components beta2-glycoprotein I and heat-shock proteins as risk factors for acute cerebral ischemia. Arq Neuropsiquiatr. 2003 Sep;61(3B):757-63. Epub 2003 Oct 28. PubMed PMID: 14595478.
  34. Staub HL, Souza F, Chan EK, von Mühlen CA. Anti-Golgi antibodies in adult Still's disease. Clin Exp Rheumatol. 2003 Mar-Apr;21(2):275-6. PubMed PMID: 12747298.
  35. Von Mühlen D, Morton D, Von Mühlen CA, Barrett-Connor E. Postmenopausal estrogen and increased risk of clinical osteoarthritis at the hip, hand, and knee in older women. J Womens Health Gend Based Med. 2002 Jul-Aug;11(6):511-8. PubMed PMID: 12225625.
  36. Lopes MH, Ludwig E, do Amaral BB, Francisconi CF, von Mühlen CA. Motor activity of the gallbladder in systemic sclerosis. Am J Gastroenterol. 1999 Dec;94(12):3487-91. PubMed PMID: 10606308.